In which direction does the ribosome move along the mRNA during translocation?

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Study for the DAT Bootcamp Molecular Genetics Test. Enhance your knowledge with flashcards and multiple-choice questions, each offering hints and explanations. Prepare effectively for your exam!

Multiple Choice

In which direction does the ribosome move along the mRNA during translocation?

Explanation:
During translocation the ribosome shifts along the mRNA in the 5' to 3' direction. After the new peptide bond forms, the ribosome moves one codon downstream, so the tRNA in the A site moves to the P site and the tRNA in the P site moves to the E site (and exits), while the mRNA slides so the next codon is positioned in the A site for decoding. This 5'→3' movement along the mRNA ensures the reading frame advances correctly with each codon.

During translocation the ribosome shifts along the mRNA in the 5' to 3' direction. After the new peptide bond forms, the ribosome moves one codon downstream, so the tRNA in the A site moves to the P site and the tRNA in the P site moves to the E site (and exits), while the mRNA slides so the next codon is positioned in the A site for decoding. This 5'→3' movement along the mRNA ensures the reading frame advances correctly with each codon.

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